Education

A major mission of the lab is to train the next generation of scientists and physician-scientists in the field of mitochondria and metabolism in a supportive environment.  The lab has trained and currently training graduate PhD students and MD/PhD student- total of 25 (14F/11M).  Dr. Chandel has received the Clarence Ver Steeg Faculty Mentor Award, which recognizes individual faculty members from any department throughout Northwestern University for their outstanding efforts in supporting and encouraging the academic and professional development of graduate students.  The lab has also trained and currently training post-doctoral fellows-total of 16 (10F/6M). 

Dr. Chandel has written an introductory book on metabolism, “Navigating metabolism” (CSHL press 2015). See links:

https://www.cshlpress.com/default.tpl?cart=1658764812473515954&fromlink=T&linkaction=full&linksortby=oop_title&--eqSKUdatarq=1037

 

https://www.amazon.com/Navigating-Metabolism-Navdeep-Chandel/dp/1621821293

 

We have continued to write review articles/perspectives that help disseminate our ideas in literature. Here is a recent list of reviews/perspectives.

 

  1. Chandel NS, Tuveson DA. The promise and perils of antioxidants for cancer patients. N Engl J Med. 2014 Jul 10;371(2):177-8.

  2. DeBerardinis RJ, Chandel NS.   We need to talk about the Warburg effect. Nature Metabolism 2020 Feb;2(2):127-129. PMID: 32694689 

  3. Martínez-Reyes I, Chandel NS. Cancer metabolism: looking forward. Nat Rev Cancer. 2021 Oct;21(10):669-680. Epub 2021 Jul 16. PMID: 34272515 

  4. Steinert EM, Vasan K, Chandel NS.   Mitochondrial Metabolism Regulation of T Cell-Mediated Immunity. Annu Rev Immunol. 2021 Apr 26;39:395-416. PMID: 33902315 

  5. Chakrabarty RP, Chandel NS. Mitochondria as Signaling Organelles Control Mammalian Stem Cell Fate. Cell Stem Cell. 2021 Mar 4;28(3):394-408. PMID: 33667360 

  6. Vasan K, Werner M, Chandel NS. Mitochondrial Metabolism as a Target for Cancer Therapy. Cell Metab. 2020 Sep 1;32(3):341-352. Epub 2020 Jul 14.  PMID: 32668195 

  7. Lee P, Chandel NS, Simon MC.   Cellular adaptation to hypoxia through hypoxia inducible factors and beyond. Nat Rev Mol Cell Biol. 2020 May;21(5):268-283. PMID: 32144406

  8. Martínez-Reyes I, Chandel NS.   Mitochondrial TCA cycle metabolites control physiology and disease. Nature Commun. 2020 Jan 3;11(1):102. doi: 10.1038/s41467-019-13668-3.PMID: 31900386