Chandel Lab

The MitoWorld initiative aims to bring together top researchers in the field and establish task forces to address key questions and prioritize research funding. The goal is to create a more coherent landscape of basic mitochondrial science and foster collaboration among researchers working on different diseases and aspects of mitochondrial biology.

Now in its 11th year, the Lurie Prize in Biomedical Sciences recognizes outstanding achievement by promising scientists aged 52 or younger. The prize includes a $50,000 honorarium to each awardee, made possible by a donation to the FNIH by philanthropist Ann Lurie, President of the Ann and Robert H. Lurie Foundation and President of Lurie Holdings, Inc.

The 2023 winners, selected by a distinguished jury of biomedical researchers, chaired by Solomon H. Snyder, MD, Vice Chairman of the FNIH Board, were honored at the FNIH 11th Annual Awards Ceremony on the evening of October 18, 2023, in Washington, D.C.

This video presents the full fireside conversation between FNIH President & CEO Dr. Julie L. Gerberding and the 2023 winners, Dr. Navdeep Chandel and Dr. Vamsi Mootha, taken from the full recording of the 2023 Awards Ceremony.

In Episode #226 of SmartDrugSmarts, Dr. Chandel shares his research into the subcellular world of mitochondria, ATP, the Krebs Cycle — and how these esoteric interests translate up into real-world lifespan and quality-of-life differences for us big, adult mammals.

Metabolism has a direct impact on aging and the way we look. On today’s  episode, we discuss the current research around metabolism with experts  Dr. Heather Christofk and Dr. Navdeep Chandel and dive into hair  follicle stem cell activation, a lesson on hyaluronic acid from naked  mole rats, and the complexity of addressing oxidative stress and the  skin’s extracellular matrix.

Mitochondria  are widely known as cellular “powerhouses” for their role in producing  energy for cells. But pioneering research from Northwestern Medicine  investigators over the last 20 years has proven mitochondria are also  major players in lung disease, cancer, brain disease and immune-related  diseases. Navdeep Chandel, PhD, a 2023 recipient of the Lurie Prize in Biomedical Sciences by the Foundation for the National Institutes of Health, leads this  research. In this episode he discusses how his team’s recent findings  could advance the design and implementation of new therapies.

Mitochondria are often referred to as the “powerhouses” of the cell, but  as scientists gain a greater understanding of these essential  organelles, they are coming to discover they play a more expansive role  in health and disease. The Foundation for the National Institutes of  Health named Navdeep Chandel a co-recipient of the 2023 Lurie Prize in  Biomedical Sciences for his research that revealed how mitochondria  function as signaling organelles that control the body’s normal  functions and impact diseases, including cancer and inflammation. We  spoke to Chandel, professor of medicine in the Division of Pulmonary and  Critical Care and of biochemistry and molecular genetics at the  Feinberg School of Medicine, about the state of our understanding of  mitochondria, why drug developers are pursuing therapies to target  mitochondria across a broad range of diseases, and the need for a  concerted effort to conduct fundamental research to better understand  the biology of this organelle.

In this podcast episode of The Peter Attia Drive, Navdeep Chandel, PhD discusses the role of mitochondria and metabolism in health and disease. Nav also provides insights into the mitochondria as signaling organelles, antioxidants, and Metformin's multifaceted effects on human health, among many topics related to well-being.